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They note that one mechanism by which minocycline likely attenuates depressive symptoms is via modulation of nitric oxide.

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however, the bnf advises avoiding tetracyclines, except doxycycline and minocycline, even in mild impairment.

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minocycline has been reported to cause or precipitate pseudotumor cerebri, the hallmark of which is papilledema.

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minocycline corrects early, pre-plaque neuroinflammation and inhibits bace-1 in a transgenic model of alzheimer s disease-like amyloid pathology.

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