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Clopidogrel bisulfate working standard was supplied by dr reddy s laboratories ltd hyderabad, india , while clopidogrel-d4 hydrogen sulfate internal standard is was supplied by trc north york, canada .

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the mean auc of the active metabolite of clopidogrel was reduced by approximately 14 mean auc ratio was 86 , with 90 ci of 80 to 92 when prevacid was coadministered compared to administration of clopidogrel alone.

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clopidogrel is metabolized to its active metabolite by cytochrome p-450 cyp isoenzyme 2c19 cyp2c19 .

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in summary i expect brilinta to be a niche product used in uncommon circumstances once clopidogrel becomes available as an inexpensive generic.

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