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during diltiazem coadministration, monitor quinidine serum concentrations and therapeutic response; adjust quinidine dosage if needed.

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diltiazem lp is an inhibitor of cyp3a4 and has been shown to increase significantly the auc of some statins.

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high-performance liquid chromatography analysis was undertaken with 36 preparations of compounded 2 topical diltiazem that were gathered from 12 different independent retail pharmacies in a major metropolitan area.

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complex interactions can be expected with coadministered with diltiazem or verapamil, as both are substrates and inhibitors of cyp3a4.


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