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Although indinavir s product labeling states that coadministration of certain cyp3a substrates that have the potential for serious adverse events with elevated concentrations are contraindicated, the interaction between ketoconazole a potent cyp3a inhibitor and eliglustat was studied during clinical trials.

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background indinavir, a protease inhibitor widely used to treat patients with hiv infection, has been associated with nephrolithiasis.

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lumacaftor; ivacaftor dosage adjustment is not required when indinavir is started in a patient already taking lumacaftor; ivacaftor.


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